Modeling and Numerical Simulation of Tissue Engineering Scaffold 3D Printing Process

Authors

Congping Chen, College of Mechanical & Power Engineering, China Three Gorges University, Yichang, 443002, China;
Jieguang Huang, College of Mechanical & Power Engineering, China Three Gorges University, Yichang, 443002, China;
Hu Qiong, College of Mechanical & Power Engineering, China Three Gorges University, Yichang, 443002, China;
Yanhua Ran, College of Mechanical & Power Engineering, China Three Gorges University, Yichang, 443002, China;
Li Bo, College of Mechanical & Power Engineering, China Three Gorges University, Yichang, 443002, China;

Abstract

Abstract: In the process of tissue engineering scaffold fabrication using injecting 3D printing, the viscous fluid material is extruded out with a style of microfilament, which is deposited on a substrate layer by layer. The materials spread, pile up, remelt and solidify as a consequence of the couple effects of gravity, surface tension, viscous force and solidification drag force. Aiming at the above issues, the forming process of scaffold with homogeneously-sized space pores is studied with a CFD approach to research the pore forming mechanism. The results show that the viscous fluid is cooled mainly by the substrate, and heat transfers from the top to the bottom in the scaffold. The fluid’s temperature is lower and the solidification ratio is higher where it’s closer to the substrate. In this paper, under the conditions mentioned, the effect of solidification drag is greater than the viscous force and the surface tension. The viscous fluid spreads and solidifies subsequently when depositing on the substrate. The pores size decreases with the spreading time. With the scaffold layers rising, the overall trend of porosity decreases.

Recommended Citation

Chen, Congping; Huang, Jieguang; Qiong, Hu; Ran, Yanhua; and Bo, Li (2019) "Modeling and Numerical Simulation of Tissue Engineering Scaffold 3D Printing Process," Journal of System Simulation: Vol. 30: Iss. 3, Article 30.
DOI: 10.16182/j.issn1004731x.joss.201803030
Available at: https://dc-china-simulation.researchcommons.org/journal/vol30/iss3/30

First Page

1008

DOI Link

https://doi.org/10.16182/j.issn1004731x.joss.201803030

Last Page

1016

CLC

O351.2

Recommended Citation

Chen Congping, Huang Jieguang, Hu Qiong, Ran Yanhua, Li Bo. Modeling and Numerical Simulation of Tissue Engineering Scaffold 3D Printing Process[J]. Journal of System Simulation, 2018, 30(3): 1008-1016.

DOI

10.16182/j.issn1004731x.joss.201803030